Rickettsia conorii Transcriptional Response within Inoculation Eschar
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چکیده
منابع مشابه
Rickettsia conorii Transcriptional Response within Inoculation Eschar
BACKGROUND Rickettsia conorii, the causative agent of the Mediterranean spotted fever, is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within infected skin is critical for our understanding of rickettsi...
متن کاملFatal Rickettsia conorii subsp. israelensis Infection, Israel
Underdiagnosis of fatal spotted fever may be attributed to nonspecific clinical features and insensitive acute-phase serologic studies. We describe the importance of molecular and immunohistochemical methods in establishing the postmortem diagnosis of locally acquired Israeli spotted fever due to Rickettsia conorii subsp. israelensis in a traveler returning to Israel from India.
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Small regulatory RNAs comprise critically important modulators of gene expression in bacteria, yet very little is known about their prevalence and functions in Rickettsia species. R. conorii, the causative agent of Mediterranean spotted fever, is a tick-borne pathogen that primarily infects microvascular endothelium in humans. We have determined the transcriptional landscape of R. conorii durin...
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3. Santos MR, Ghandi S, Vogler M, Hanna BA, Holzman RS. Suspected diphtheria in a Uzbek national; isolation of C. pseudodiphtheriticum resulted in a false positive presumptive diagnosis. Clin Infect Dis 1996;22:735. 4. Izurieta HS, Strebel PM, Youngblood T, Hollis DG, Popovic T. Exudative pharyngitidis possibly due to C. pseudodiphtheriticum, a new challenge in the differential diagnosis of dip...
متن کاملWhy Are There So Few Rickettsia conorii conorii-Infected Rhipicephalus sanguineus Ticks in the Wild?
BACKGROUND Rickettsia conorii conorii is the etiological agent of Mediterranean spotted fever, which is transmitted by the brown dog tick, Rhipicephalus sanguineus. The relationship between the Rickettsia and its tick vector are still poorly understood one century after the first description of this disease. METHODOLOGY/PRINCIPAL FINDINGS An entomological survey was organized in Algeria to co...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0003681